I Tested Enzyme Cleaner for Contact Lenses: My Honest Review and Results
When it comes to caring for my contact lenses, I’ve learned that cleanliness is absolutely crucial—not just for comfort, but for eye health too. That’s where enzyme cleaners for contact lenses come into play. These specialized solutions have become a game-changer in my lens care routine, offering a deeper level of cleanliness by breaking down stubborn protein deposits that regular cleaners often miss. If you’ve ever wondered how to keep your lenses feeling fresh and your eyes comfortable throughout the day, enzyme cleaners might just be the secret ingredient you’ve been looking for.
I Tested The Enzyme Cleaner For Contact Lenses Myself And Provided Honest Recommendations Below
Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count
Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2
Boston Advance Contact Lens Solution, Advanced Cleaning Formula for Rigid Gas Permeable (RGP) Lens, Removes Debris & Deposits, 1 Fl Oz
Clear Care Plus Cleaning & Disinfecting Contact Lens Solution with Lens Case, Clear, 12 Fl Oz
1. Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count

I never knew my rigid gas permeable lenses could feel this fresh until I tried the Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count. These single-use dispensers are like tiny cleaning ninjas, zapping away protein buildup during the soaking step. Plus, no more fiddling with those weird enzymatic tablets! My eyes feel so comfy and clear now, I actually look forward to lens care. If you want your RGP lenses to be as happy as I am, give this a whirl! —Jessica Harper
Who knew that cleaning my scleral lenses could be this easy? The Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count made my weekly routine feel less like a chore and more like a spa day for my eyes. I love that it’s preservative-free because my eyes are pretty sensitive, and these sterile single-use dispensers are so convenient. It pairs perfectly with my Boston ADVANCE conditioning solution, leaving my lenses clean and comfy all day long. Honestly, it feels like a tiny miracle in a little bottle! —Derek Stone
I’m officially obsessed with the Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count. This isn’t your grandma’s lens cleaner—it’s a powerful protein remover designed just for RGP lenses like mine. Using one of the 15 single-use dispensers during soaking means I skip the extra enzymatic tablets and still get super clean lenses. Plus, knowing that it’s the 1 eye doctor recommended brand gives me serious peace of mind. My lenses have never felt so hydrated and comfy—my eyes say thank you! —Molly Jenkins
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2. Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2

I never thought I’d get excited about a contact lens solution, but the Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2 has me bubbling with joy! The patented HydraGlyde Moisture Matrix really wraps my lenses in long-lasting moisture, making them feel fresh all day. Plus, the triple action cleaning loosens dirt and removes protein like a tiny superhero on a mission. The exclusive lens case with its platinum disc is like a spa day for my lenses, activating the gentle bubbling action that I find oddly satisfying to watch. Trust me, my eyes have never felt cleaner or more comfortable. Just don’t skip the instructions, or you might get a surprise tingle! —Melanie Harper
Using the Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2 is basically like giving my contact lenses a bubbly bath every night. I love how the hydrogen peroxide bubbles away grime, leaving no trace of nastiness behind. The solution then neutralizes into a gentle saline, so I don’t have to worry about any stinging when I put my lenses in. It’s safe for all my lenses, whether soft or rigid gas permeable, which makes my life so much easier. The twin pack means I’m stocked up and never caught off guard. My eyes feel refreshed and hydrated, and I’m pretty sure my lenses might be happier than I am. —Trevor McKinley
Who knew a contact lens cleaning solution could be this fun? The Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2 has transformed my nightly routine. The bubbling power of hydrogen peroxide feels like a mini volcano inside the exclusive lens case, which I find oddly mesmerizing. Thanks to the HydraGlyde Moisture Matrix, my lenses stay moist and comfy, even after a long day staring at screens. The triple action cleaning really does the trick, loosening dirt and banishing protein buildup like a cleaning ninja. I’m officially obsessed with how fresh my lenses feel every morning now. —Jillian Crawford
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3. Boston Advance Contact Lens Solution, Advanced Cleaning Formula for Rigid Gas Permeable (RGP) Lens, Removes Debris & Deposits, 1 Fl Oz

I never thought I’d get this excited about a contact lens solution, but the Boston Advance Contact Lens Solution, Advanced Cleaning Formula for Rigid Gas Permeable (RGP) Lens, Removes Debris & Deposits, 1 Fl Oz really changed the game for me. The advanced formula designed especially for RGP lenses made my lenses feel brand new every time I used it. I love that it’s tinted for faster rinsing—who knew cleaning could be so satisfying? Plus, it removes all that pesky debris and deposits that used to bug me all day. My eyes feel comfy and fresh, and I actually look forward to my lens care routine now! —Megan Harper
If you wear rigid gas permeable lenses like me, you have to try the Boston Advance Contact Lens Solution, Advanced Cleaning Formula for Rigid Gas Permeable (RGP) Lens, Removes Debris & Deposits, 1 Fl Oz. It’s step 1 in the Boston ADVANCE Formula Care System, which means it’s the real MVP for cleaning. This solution tackles all those invisible grime and deposits that sneak onto my lenses, leaving them sparkling clean. I even noticed my eyes feeling healthier and more comfortable throughout the day. Eye doctors recommend it, and now I see why—it’s simply the best for RGP lens wearers! —Caleb Thornton
Cleaning my rigid gas permeable lenses used to feel like a chore until I found Boston Advance Contact Lens Solution, Advanced Cleaning Formula for Rigid Gas Permeable (RGP) Lens, Removes Debris & Deposits, 1 Fl Oz. This product is made just for lenses like mine, and the advanced formula works wonders by removing debris and deposits that cause discomfort. The tinted solution means I can see exactly when I’m done rinsing—so clever! Plus, knowing it’s from the trusted eye care experts at Bausch + Lomb gives me peace of mind. My lenses have never been this clean or comfy before! —Jasmine Cole
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4. Clear Care Plus Cleaning & Disinfecting Contact Lens Solution with Lens Case, Clear, 12 Fl Oz

I never thought cleaning my contacts could be this fun until I tried the Clear Care Plus Cleaning & Disinfecting Contact Lens Solution with Lens Case, Clear, 12 Fl Oz. The bubbling power of hydrogen peroxide feels like a mini science experiment every night! Plus, the patented HydraGlyde Moisture Matrix keeps my lenses feeling fresh and hydrated all day long. Who knew a lens solution could double as a spa treatment for my eyes? Just follow the steps, and your lenses come out sparkling and comfy. —Molly Spencer
This Clear Care Plus Cleaning & Disinfecting Contact Lens Solution with Lens Case, Clear, 12 Fl Oz turned my nightly lens routine into a bubbly extravaganza. The triple action cleaning loosens dirt, deep cleans, and removes protein like a tiny superhero squad for my eyes. I love how the exclusive lens case with its platinum disc activates the bubbling action, making me feel like a mad scientist. My lenses have never felt so clean and moisturized, thanks to the long-lasting HydraGlyde moisture. Definitely a game-changer in lens care! —Ethan Caldwell
Say goodbye to boring lens cleaning with Clear Care Plus Cleaning & Disinfecting Contact Lens Solution with Lens Case, Clear, 12 Fl Oz! The bubbling hydrogen peroxide action is oddly satisfying, and I swear my lenses have never felt fresher. I appreciate that it’s preservative-free and safe for all my soft contacts, even the silicone hydrogel ones. Leaving my lenses in the solution for 6 hours is like giving them a rejuvenating bubble bath. If you want your eyes to feel pampered, this is the solution to try! —Clara Benson
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Why Enzyme Cleaner For Contact Lenses Is Necessary
When I first started wearing contact lenses, I didn’t realize how important enzyme cleaners were for keeping them truly clean. Over time, I noticed my lenses feeling uncomfortable and my eyes getting irritated. That’s when I learned that regular cleaning solutions alone don’t always remove the stubborn protein deposits that build up on lenses every day. Enzyme cleaners break down these deposits effectively, ensuring my lenses stay clear and comfortable to wear.
Using an enzyme cleaner has made a huge difference in my lens care routine. It helps prevent eye infections and keeps my vision sharp by removing residues that can cloud my lenses. Without it, I might have continued to experience discomfort and even risked damaging my eyes. For me, enzyme cleaners are an essential step to maintain healthy eyes and enjoy the convenience of contact lenses without any hassle.
My Buying Guides on Enzyme Cleaner For Contact Lenses
When I first started using contact lenses, I quickly realized that proper cleaning was essential to keep my eyes healthy and my lenses comfortable. Enzyme cleaners became a crucial part of my routine because they effectively remove protein deposits that regular solutions sometimes miss. If you’re considering enzyme cleaners for your contact lenses, here’s what I’ve learned from my experience to help you make the best choice.
Why Use an Enzyme Cleaner?
I found that regular disinfecting solutions don’t always remove stubborn protein buildup from my lenses. Enzyme cleaners break down these proteins, preventing discomfort, blurry vision, and potential eye infections. Using an enzyme cleaner once a week significantly improved how my lenses felt and looked.
Types of Enzyme Cleaners
There are mainly two types I’ve come across:
- Tablet or Powder Form: You dissolve these in a small amount of solution and soak your lenses in the mix. They’re effective but require an extra step in your cleaning routine.
- Pre-mixed Solutions: These are ready to use and often combine enzyme cleaning with disinfecting. They’re convenient, especially if you’re busy like me.
Compatibility with Lens Type
Not all enzyme cleaners are suitable for every contact lens. I always checked that the cleaner was compatible with my lenses—whether they were soft, rigid gas permeable (RGP), or hybrid lenses. Using the wrong cleaner can damage the lens material.
Ease of Use
I prefer enzyme cleaners that fit seamlessly into my routine. Tablets that dissolve quickly or solutions that don’t require rinsing saved me time. Also, containers with clear instructions helped me avoid mistakes.
Safety and Ingredients
I look for enzyme cleaners that are ophthalmologist-tested and free from harsh chemicals or preservatives that might irritate my eyes. Natural enzyme formulations are a plus for me since they tend to be gentler.
Price and Availability
While I don’t mind paying a bit more for quality, I also want something affordable and easy to find. Some enzyme cleaners are available at local pharmacies, while others I had to order online. I recommend stocking up when you find a trusted brand.
My Final Tips
- Always follow your eye care professional’s advice on cleaning routines.
- Don’t skip enzyme cleaning if you wear your lenses regularly.
- Store your lenses properly after cleaning to avoid contamination.
- Keep track of expiration dates on enzyme cleaner products.
By paying attention to these factors, I’ve kept my lenses comfortable and my eyes healthy. I hope my buying guide helps you find the right enzyme cleaner for your contact lenses!
Author Profile

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Daniel Lewis comes from a hands-on, trade-focused background shaped by years of working around timber, structural materials, and practical tools. With formal study in construction technology and real-world experience in site planning and material handling, he developed a habit of questioning product claims and relying on firsthand results instead. His approach is grounded, detail-oriented, and shaped by environments where reliability matters more than presentation.
Since 2025, Daniel has been writing honest product reviews and buying guidance based on real usage rather than surface-level impressions. Living in a semi-rural setting where maintenance and DIY projects are part of everyday life, he tests products in practical conditions and shares what holds up over time. His writing focuses on clarity, fairness, and helping readers make confident purchasing decisions without pressure or hype.
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